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L'uso concomitante degli oppioidi con medicinali sedativi occur le benzodiazepine o i farmaci correlati aumenta il rischio di sedazione, depressione respiratoria, coma e morte, a causa degli effetti depressivi additivi sul SNC. La dose e la durata dell'uso concomitante devono essere limitati (vedere paragrafo 4.four).The controversy arrives as bein… Read More

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